Patients Claim Ovarian Tumors Caused by Talc-Based Powder

Three previous users of talc-based baby powder developed serious cases of epithelial ovarian tumors, causing them to sue over the powder’s alleged carcinogenic properties. The tumors had a highly abnormal cell count, making them malignant and causing the women to endure severe medical costs and complications. After deciding to take the baby powder manufacturing company to court, an expert who could analyze tissue slides for particles of talc was needed to opine on whether there was a connection between the product and the cancer.

Question(s) For Expert Witness

1. Would you able to examine slides of ovarian tissue and identify any birefringent particles like talc?

Expert Witness Response E-053346

My chairman and I could work together to analyze the particles and deem whether they are carcinogenic. I can identify particles in tissue using H&E staining of paraffin sections to detect birefringent particles, and if positive, I would examine the same tissue by scanning electron microscopy microprobe analysis to detect aluminum silicate. My colleague, a pathologist, would then review the slides to see whether there was any evidence of ovarian carcinoma.